Genistein induces maturation of cultured human breast cancer cells and prevents tumor growth in nude mice.

doi:10.1093/ajcn/68.6.1426S

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Article

Genistein induces maturation of cultured human breast cancer cells and prevents tumor growth in nude mice.

The American journal of clinical nutrition - 1 Dec 1998

Constantinou A I, Krygier A E, Mehta R R

Abstract excerpt

Results of recent studies in animal models of mammary carcinogenesis showed that the soybean isoflavone genistein is a chemopreventive agent. The objective of the present study was to determine whether soybean isoflavones can be used for the prevention of human breast carcinogenesis. Human adenoc...

Topics

Adenocarcinoma
Animals
Anticarcinogenic Agents
Breast Neoplasms
Cell Division
Cell Transformation, Neoplastic
Genistein
Humans
Isoflavones
Mammary Neoplasms, Experimental
Mice
Mice, Inbred BALB C
Mice, Nude
Phenotype
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 9848511
DOI: 10.1093/ajcn/68.6.1426S

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9848511-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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