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Plasmid-Driven Formation of Influenza Virus-Like Particles

1 Jan 2000

Abstract excerpt

We established a plasmid-based system for generating infectious influenza virus-like particles entirely from cloned cDNAs. Human embryonic kidney cells (293T) were transfected with plasmids encoding the influenza A virus structural proteins and with a plasmid encoding an influenza virus-like viral RNA (vRNA) which contained an antisense copy of the cDNA for green fluorescence protein (GFP) flanked by an RNA...

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PMID: 10590147
DOI: 10.1128/jvi.74.1.547-551.2000

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