Article
Key residues revealed in a major conformational epitope of the U1-70K protein.
Proceedings of the National Academy of Sciences of the United States of America - 7 Dec 1999
Welin Henriksson E, Wahren-Herlenius M, Lundberg I, Mellquist E, Pettersson I
Abstract excerpt
Epitopes depending on three-dimensional folding of proteins have during recent years been acknowledged to be main targets for many autoantibodies. However, a detailed resolution of conformation-dependent epitopes has to date not been achieved in spite of its importance for understanding the complex interaction between an autoantigen and the immune system. In analysis of immunodominant epitopes of the U1-70K...
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