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Article

Genomic characterization of POS5, the Saccharomyces cerevisiae mitochondrial NADH kinase.

Mitochondrion - 1 Apr 2006

Shianna Kevin V, Marchuk Douglas A, Strand Micheline K

Abstract excerpt

Disruption of the Saccharomyces cerevisiae mitochondrial NADH kinase POS5 increases the mitochondrial mutation rate 50-fold. Whereas most multicellular eukaryotic genomes have one NADH kinase gene, the yeast genome contains three distinct genes encoding NAD/H kinase activity. To determine if all three genes are essential for viability we constructed combinations of gene knockouts. We show that only the...

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PMID: 16621727
DOI: 10.1016/j.mito.2006.02.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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