Article
A clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancer
1 Mar 1996
Abstract excerpt
Overexpression of cyclin D1 is frequently found in various types of human tumours and results from clonal rearrangement and/or amplification involving chromosomal region 11q13. In order to evaluate the pathological relevance of cyclin D1 overexpression in human breast cancer, we generated a polyclonal antiserum against the carboxy-terminal part of the cyclin D1 protein. After affinity purification, the antiserum...
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