Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic significance of cyclin D1 protein expression and gene amplification in invasive breast carcinoma

15 Nov 2017

Abstract excerpt

The oncogenic capacity of cyclin D1 has long been established in breast cancer. CCND1 amplification has been identified in a subset of patients with poor prognosis, but there are conflicting data regarding the predictive value of cyclin D1 protein overexpression. This study was designed to analyze the expression of cyclin D1 and its correlation with CCND1 amplification and their prognostic implications in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Cancer Treatment Studies
Share to Cancer Genomics and Diagnostics
Share to Cancer-related Molecular Pathways

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29140993
DOI: 10.1371/journal.pone.0188068

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic significance of cyclin D1 protein expression and gene amplification in invasive breast carcinomaPMID 29140993Read ↗

CCND1 amplification and cyclin D1 expression in breast cancer and their relation with proteomic subgroups and patient outcomeSemantic proximity Read ↗

The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumoursSemantic proximity Read ↗

Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysisSemantic proximity Read ↗

Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining.Semantic proximity Read ↗

An update on the implications of cyclin D1 in oral carcinogenesisSemantic proximity Read ↗

Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcomeSemantic proximity Read ↗

Cyclin D1 in invasive breast carcinoma: favourable prognostic significance in unselected patients and within subgroups with an aggressive phenotype.Semantic proximity Read ↗

Amplification of cyclin D1 in squamous cell carcinoma of the head and neck and the prognostic value of chromosomal abnormalities and cyclin D1 overexpression.Semantic proximity Read ↗

Cyclin-D1-gene amplification is a more potent prognostic factor than its protein over-expression in human head-and-neck squamous-cell carcinomaSemantic proximity Read ↗

Cyclin D1 in Cancer: A Molecular Connection for Cell Cycle Control, Adhesion and Invasion in Tumor and StromaSemantic proximity Read ↗

Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer.Semantic proximity Read ↗

The prognostic significance and value of cyclin D1, CDK4 and p16 in human breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.