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Article

Human phosphodiesterase 8A splice variants: cloning, gene organization, and tissue distribution.

Gene - 12 Dec 2001

Wang P, Wu P, Egan R W, Billah M M

Abstract excerpt

We have cloned cDNAs representing five full-length human phosphodiesterase (PDE) 8A splice variants (PDE8As 1-5) from testis and T cells. PDE8A1 encodes a hydrophilic protein of 829 amino acids, containing an N-terminal REC domain, a PAS domain, and a C-terminal catalytic domain. PDE8A2 encodes a protein of 783 amino acids, identical to PDE8A1 but lacking the PAS domain. PDE8A3 encodes a shorter protein...

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Identifiers

PMID: 11738832
DOI: 10.1016/s0378-1119(01)00783-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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