Article
Tumour necrosis factor polymorphisms and susceptibility to follicular lymphoma.
British journal of haematology - 1 Nov 1999
Fitzgibbon J, Grenzelias D, Matthews J, Lister T A, Gupta R K
Abstract excerpt
Follicular lymphoma is characterized in 85% of patients by the presence of a t(14;18) chromosomal translocation that results in overproduction of BCL2. In this study the distribution of high and low expressing TNF alleles at the TNF (-308) and LTalpha (+252) polymorphic sites in 121 patients with follicular lymphoma and 88 control individuals has been analysed. A reduction in high expressing haplotypes in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
