Article
Polymorphism in the second intron of dopamine receptor D4 gene in humans and apes.
Biochemical and biophysical research communications - 16 Apr 2004
Shimada Makoto K, Inoue-Murayama Miho, Ueda Yuko, Maejima Masami, Murayama Yuichi, Takenaka Osamu, Hayasaka Ikuo, Ito Shin'ichi
Abstract excerpt
The dopamine receptor D4 (DRD4) has received increasing research attention in behavioral science, psychiatry, and psychopharmacology. However, the number of available genetic markers for primates is still insufficient. We identified a novel variation/polymorphism in the second intron of DRD4 in humans based on the survey of 210 Japanese: a 6bp insertion (allele frequency: 0.002) and 8bp deletion (0.024); however,...
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