Article
Development of early postnatal peripheral nerve abnormalities in Trembler‐J and PMP22 transgenic mice
1 Oct 1999
Abstract excerpt
Mutations in the gene for peripheral myelin protein 22 (PMP22) are associated with peripheral neuropathy in mice and humans. Although PMP22 is strongly expressed in peripheral nerves and is localised largely to the myelin sheath, a dual role has been suggested as 2 differentially expressed promoters have been found. In this study we compared the initial stages of postnatal development in transgenic mouse models...
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