Article
Non-invasive transgenic mouse genotyping using stool analysis.
FEBS letters - 26 Nov 1999
Broome R L, Feng L, Zhou Q, Smith A, Hahn N, Matsui S M, Omary M B
Abstract excerpt
Commonly applied genotyping of transgenic mice involves using tail or ear biopsies which may cause discomfort to the animal. We tested the possibility of polymerase chain reaction (PCR)-based mouse genotyping using stool specimens from three transgenic mouse lines that overexpress 10-18 transgene copies of human keratin polypeptide 18, as compared to genotyping using tail biopsies. Stool specimens were obtained...
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