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Article

The genetic epidemiology of early-onset epithelial ovarian cancer: a population-based study.

American journal of human genetics - 1 Dec 1999

Stratton J F, Thompson D, Bobrow L, Dalal N, Gore M, Bishop D T, Scott I, Evans G, Daly P, Easton D F, Ponder B A

Abstract excerpt

We conducted a population-based study to determine the contribution of germline mutations in known candidate genes to ovarian cancer diagnosed at age <30 years. Women with epithelial ovarian cancer were identified through cancer registries. DNA samples were analyzed for mutations in BRCA1, the "ovarian cancer-cluster region" (nucleotides 3139-7069) of BRCA2, and the mismatch-repair genes hMSH2 and hMLH1. Probable...

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Source

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Identifiers

PMID: 10577927
DOI: 10.1086/302671
PMCID: PMC1288384

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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