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Article

Long-term risk of cancer among the first-degree relatives of epithelial ovarian cancer patients: A cohort study with 48 years of follow up.

Acta obstetricia et gynecologica Scandinavica - 1 Mar 2023

Kotaniemi-Talonen Laura, Pukkala Eero, Aittomäki Kristiina, Auranen Annika

Abstract excerpt

INTRODUCTION: The long-term risk of cancer among first-degree relatives of ovarian cancer patients, especially their offspring, is of apparent clinical importance. Risks caused by known inherited factors such as BRCA1 or BRCA2 pathogenic variants are well established, but these account for only about 15% of ovarian cancer cases. Less is known about the possible familial risks of sporadic ovarian cancers. MATERIAL...

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Identifiers

PMID: 36645194
DOI: 10.1111/aogs.14504
PMCID: PMC9951276

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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