Article
Genetic variation in the corticotrophin-releasing factor receptors: identification of single-nucleotide polymorphisms and association studies with obesity in UK Caucasians.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Mar 2004
Challis B G, Luan J, Keogh J, Wareham N J, Farooqi I S, O'Rahilly S
Abstract excerpt
OBJECTIVE: To investigate whether genetic variation at the loci encoding the corticotropin-releasing factor receptors-1 and -2 (CRF-R1 and CRF-R2) contributes to human obesity. DESIGN: The coding region of the CRF-R1 and CRF-R2 genes was screened in 51 severely obese children (body mass index (BM...
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