Article
Novel variants in the promoter region of the CREB gene in schizophrenic patients.
Journal of human genetics - 1 Jan 1999
Kawanishi Y, Harada S, Tachikawa H, Okubo T, Shiraishi H
Abstract excerpt
Cyclic AMP-responsive element-binding protein (CREB) is one of the messenger molecules involved in intracellular signal transduction pathways used by most dopamine and serotonin receptor subtypes. In addition, CREB stimulates the expression of a number of genes, alterations in the expression of which may be associated with schizophrenia. The promoter region of the human CREB gene was therefore analyzed to...
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