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Article

Enhancement of fcgamma receptor-mediated phagocytosis by transforming mutants of Cbl.

Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 1999

Sato N, Kim M K, Schreiber A D

Abstract excerpt

Phagocytosis mediated by FcgammaR plays an important role in host defense. The molecular events involved in this process have not been completely defined. The adapter protein Cbl has been implicated in FcgammaR signaling, but the function of Cbl in phagocytosis is unknown. Here we show that overexpression of the transforming mutants of Cbl, Cbl-70Z, and v-Cbl, but not wild-type (wt) Cbl, enhance phagocytosis...

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PMID: 10570302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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