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Article

Spatial-specific TGF-beta1 adenoviral expression determines morphogenetic phenotypes in embryonic mouse lung.

European journal of cell biology - 1 Oct 1999

Zhao J, Sime P J, Bringas P, Tefft J D, Buckley S, Bu D, Gauldie J, Warburton D

Abstract excerpt

The precise spatial-temporal role that expression and activation of transforming growth factor (TGF)-beta plays in mammalian organ morphogenesis remains incompletely understood. Using replication deficient adenoviral vectors containing engineered TGF-beta1 cDNAs, we studied the spatial effects of locally over-expressing either latent or mutated, constitutively active TGF-beta1 protein during embryonic mouse lung...

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Source

Identifiers

PMID: 10569244
DOI: 10.1016/s0171-9335(99)80040-5

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MGP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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