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Article

Activation of Transgene-specific T Cells Following Lentivirus-mediated Gene Delivery to Mouse Lung

1 Sept 2009

Abstract excerpt

Integrating lentiviral vectors based on the human immunodeficiency virus type-1 (HIV-1) can transduce quiescent cells, which in lung account for almost 95% of the epithelial cell population. Pseudotyping lentiviral vectors with the envelope glycoprotein from the Ebola Zaire virus, the lymphocytic choriomeningitis virus (LCMV), the Mokola virus, and the vesicular stomatitis virus (VSV-G) resulted in transduction...

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Identifiers

PMID: 19724265
DOI: 10.1038/mt.2009.190

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