Article
Mutations in the heatshock cognate 70 protein (hsc4) modulate Notch signaling.
European journal of cell biology - 1 Oct 1999
Hing H K, Bangalore L, Sun X, Artavanis-Tsakonas S
Abstract excerpt
In our effort to dissect the Notch signaling mechanism we have conducted a screen for mutations that reduce Notch signaling activity. We recovered nine complementation groups as modifiers of the hypomorphic Notch allele notchoid. Apart from the known Notch signaling modulators Notch, Delta and mastermind we isolated alleles in vestigial, wingless, scalloped and clipped, genes known to affect wing morphogenesis....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.