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Article

Aspirin Reduces Apolipoprotein(a) (Apo(a)) Production in Human Hepatocytes by Suppression of Apo(a) Gene Transcription

1 Nov 1999

Abstract excerpt

High serum lipoprotein(a) (Lp(a)) is a risk factor for vascular disorders. Our preliminary observations suggest that, in some patients with coronary heart disease with high serum Lp(a) levels, administration of aspirin reduced Lp(a) levels. Therefore, we aimed to analyze the effects of aspirin on the production of apo(a), the expression of apolipoprotein(a) (apo(a)) mRNA and the transcriptional activity of apo(a)...

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Identifiers

PMID: 10567380
DOI: 10.1074/jbc.274.48.34111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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