Article
Identification of a CK2 phosphorylation site in mdm2.
European journal of biochemistry - 1 Dec 1999
Götz C, Kartarius S, Scholtes P, Nastainczyk W, Montenarh M
Abstract excerpt
Mdm2 is a cellular oncoprotein the most obvious function of which is the down-regulation of the growth suppressor protein p53. It represents a highly phosphorylated protein but only little is yet known about the sites phosphorylated in vivo, the kinases that are responsible for the phosphorylation or the functional relevance of the phosphorylation status. Recently, we have shown that mdm2 is a good substrate for...
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