Article
No association between apolipoprotein A-IV codon 360 mutation and late-onset Alzheimer's disease in the Japanese population.
Dementia and geriatric cognitive disorders - 1 Jan 2000
Ji Y, Urakami K, Adachi Y, Nakashima K
Abstract excerpt
Human apolipoprotein A-IV (apoA-IV) is genetically polymorphic, the apoA-IV polymorphism being controlled by two alleles, apoA-IV1 and apoA-IV2. The association between the apoA-IV2 allele and late-onset Alzheimer's disease (LOAD) has been reported in Caucasian populations. We investigated the codon 360 mutation of the apoA-IV gene allele frequency in 173 LOAD and in 158 age-matched control subjects of the...
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