Article
Lack of association between the brain-derived neurotrophin factor (C-270T) polymorphism and late-onset Alzheimer's disease (LOAD) in Brazilian patients.
Journal of molecular neuroscience : MN - 1 Jan 2004
Nishimura Agnes L, Oliveira João R M, Mitne-Neto Miguel, Guindalini Camila, Nitrini Ricar, Bahia Valéria S, de Brito-Marques Paulo R, Otto Paulo A, Zatz Mayana
Abstract excerpt
After the identification of the apolipoprotein E gene isoform (APOE-epsilon4) as a risk factor for late-onset Alzheimer's disease (LOAD), the search for other polymorphisms associated with AD has been undertaken by many groups of investigators around the world. These studies have shown controversial results in many populations. More recently, a single nucleotide polymorphism in the promoter region of the...
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