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Article

Drosophila RhoGAP68F is a putative GTPase activating protein for RhoA participating in gastrulation.

Development genes and evolution - 1 Sept 2006

Sanny Justina, Chui Vincent, Langmann Caillin, Pereira Carla, Zahedi Baharak, Harden Nicholas

Abstract excerpt

The Rho family small GTPases Rho, Rac, and Cdc42 regulate cell shape and motility through the actin cytoskeleton. These proteins cycle between a GTP-bound "on" state and a GDP-bound "off" state and are negatively regulated by GTPase-activating proteins (GAPs), which accelerate the small GTPase's intrinsic hydrolysis of bound GTP to GDP. Drosophila RhoGAP68F is similar to the mammalian protein p50RhoGAP/Cdc42GAP,...

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Identifiers

PMID: 16609869
DOI: 10.1007/s00427-006-0067-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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