Article
Drosophila RhoGAP68F is a putative GTPase activating protein for RhoA participating in gastrulation.
Development genes and evolution - 1 Sept 2006
Sanny Justina, Chui Vincent, Langmann Caillin, Pereira Carla, Zahedi Baharak, Harden Nicholas
Abstract excerpt
The Rho family small GTPases Rho, Rac, and Cdc42 regulate cell shape and motility through the actin cytoskeleton. These proteins cycle between a GTP-bound "on" state and a GDP-bound "off" state and are negatively regulated by GTPase-activating proteins (GAPs), which accelerate the small GTPase's...
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