Article
Sequential loss of two neighboring exons of the tropoelastin gene during primate evolution.
Journal of molecular evolution - 1 Nov 1999
Szabó Z, Levi-Minzi S A, Christiano A M, Struminger C, Stoneking M, Batzer M A, Boyd C D
Abstract excerpt
Previous evidence has demonstrated the absence of exons 34 and 35 within the 3' end of the human tropoelastin (ELN) gene. These exons encode conserved polypeptide domains within tropoelastin and are found in the ELN gene in vertebrate species ranging from chickens to rats to cows. We have analyzed the ELN gene in a variety of primate species to determine whether the absence of exons 34 and 35 in humans either is...
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