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Article

Evolution of the apolipoprotein E receptor 2 gene by exon loss.

Journal of biochemistry - 1 Aug 1998

Kim H J, Kim D H, Magoori K, Saeki S, Yamamoto T T

Abstract excerpt

The apolipoprotein E receptor 2 (apoER2) gene consists of a mosaic of exons, which may have been assembled by "exon shuffling." Analysis of apoER2 transcripts in several species reveals a lost repeat in the ligand-binding domain of primate apoER2. A pseudo-exon found in the primate apoER2 genes corresponds to the lost repeat but contains a crucial deletion that leads to a translational frameshift. The pseudo-exon...

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PMID: 9685741
DOI: 10.1093/oxfordjournals.jbchem.a022134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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