Article
Evolution of the apolipoprotein E receptor 2 gene by exon loss.
Journal of biochemistry - 1 Aug 1998
Kim H J, Kim D H, Magoori K, Saeki S, Yamamoto T T
Abstract excerpt
The apolipoprotein E receptor 2 (apoER2) gene consists of a mosaic of exons, which may have been assembled by "exon shuffling." Analysis of apoER2 transcripts in several species reveals a lost repeat in the ligand-binding domain of primate apoER2. A pseudo-exon found in the primate apoER2 genes c...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Callithrix
- DNA
- Evolution, Molecular
- Exons
- Gene Deletion
- Genetic Variation
- Humans
- LDL-Receptor Related Proteins
- Ligands
- Mice
- Molecular Sequence Data
- Receptors, Lipoprotein
- Repetitive Sequences, Nucleic Acid
- Sequence Homology, Amino Acid
- Sequence Homology, Nucleic Acid
