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Article

The 3'-untranslated region of the dystrophin gene - conservation and consequences of loss.

European journal of human genetics : EJHG - 1 Jul 2002

Greener Marc J, Sewry Caroline A, Muntoni Francesco, Roberts Roland G

Abstract excerpt

The 3'-untranslated region (3'UTR) of some vertebrate dystrophin genes shows an extraordinary degree and extent of conservation (better than that of many coding regions), a phenomenon that remains unexplained. We examine novel sequence and mutational data to explore the possible reasons for this. We show that loss of the human dystrophin 3'UTR is sufficient to cause Becker muscular dystrophy with pronounced...

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Identifiers

PMID: 12107815
DOI: 10.1038/sj.ejhg.5200822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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