Article
Clonal emergence in uremic parathyroid hyperplasia is not related to MEN1 gene abnormality.
Japanese journal of cancer research : Gann - 1 Sept 1999
Shan L, Nakamura Y, Murakami M, Nakamura M, Naito A, Kawahara K, Utsunomiya H, Mori I, Kakudo K
Abstract excerpt
It is difficult to differentiate between parathyroid neoplasia and hyperplasia. In an attempt to elucidate the clonality of uremic parathyroid hyperplasia and the molecular genetic abnormalities accounting for clonal emergence, we analyzed 20 cases of uremic parathyroid hyperplasia. Clonalities were determined using the X-chromosome-linked human androgen receptor (HUMARA) gene and the phosphoglycerate kinase...
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