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Article

Endocytic mechanisms responsible for uptake of GPI-linked diphtheria toxin receptor.

Journal of cell science - 1 Nov 1999

Skretting G, Torgersen M L, van Deurs B, Sandvig K

Abstract excerpt

We have here used diphtheria toxin as a tool to investigate the type of endocytosis used by a glycosylphosphatidylinositol-linked molecule, a glycosylphosphatidylinositol-linked version of the diphtheria toxin receptor that is able to mediate intoxication. The receptor is expressed in HeLa cells where clathrin-dependent endocytosis can be blocked by overexpression of mutant dynamin. Diphtheria toxin intoxicates...

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Source

Identifiers

PMID: 10547351
DOI: 10.1242/jcs.112.22.3899

Genes

EEA1
GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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