Article
[Beta 3 adrenergic receptor polymorphism and obesity].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 1998
Yoshida T, Umekawa T
Abstract excerpt
The beta 3-adrenoceptor plays a significant role in the control of lipolysis and thermogenesis in the brown adipose tissue of rodents and humans. In human beta 3-adrenoceptor, a Trp to Arg replacement has recently been discovered. This change which occurs at position 64, in the first coding exon,...
Topics
- Adipose Tissue
- Animals
- Body Temperature Regulation
- Diabetes Mellitus
- Humans
- Lipolysis
- Mutation
- Obesity
- Polymorphism, Genetic
- Receptors, Adrenergic, beta
- Receptors, Adrenergic, beta-3
