Article
Molecular epidemiology of Candida isolates from AIDS patients showing different fluconazole resistance profiles.
Journal of clinical microbiology - 1 Mar 1995
Lischewski A, Ruhnke M, Tennagen I, Schönian G, Morschhäuser J, Hacker J
Abstract excerpt
Thirty Candida isolates obtained from the oropharynxes of three AIDS patients were genotypically characterized. In vitro fluconazole MIC determination revealed increasing fluconazole resistances during treatment, thereby confirming the in vivo situation. Pulsed-field gel electrophoresis karyotyping, randomly amplified polymorphic DNA analysis, and hybridizations with Candida albicans repetitive element 2 were...
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