Article
Isolation of polymyxin B-susceptible mutants of Burkholderia pseudomallei and molecular characterization of genetic loci involved in polymyxin B resistance.
Antimicrobial agents and chemotherapy - 1 Nov 1999
Burtnick M N, Woods D E
Abstract excerpt
Burkholderia pseudomallei is a gram-negative bacterium that causes the disease known as melioidosis. This pathogen is endemic to Southeast Asia and northern Australia and is particularly problematic in northeastern Thailand. It has been previously reported that B. pseudomallei is resistant to the killing action of cationic antimicrobial peptides, including human neutrophil peptide, protamine sulfate,...
Topics
- Alleles
- Anti-Bacterial Agents
- Bacterial Outer Membrane Proteins
- Blotting, Western
- Burkholderia pseudomallei
- DNA, Bacterial
- Drug Resistance, Microbial
- Genetic Complementation Test
- Humans
- Lipid A