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Article

Determinants of the DNA-Binding Specificity of the Avian Homeodomain Protein, AKR

1 Oct 1999

Abstract excerpt

AKR (Avian Knotted-Related) was the first example of a vertebrate homeodomain protein with a highly divergent Ile residue at position 50 of the DNA-recognition helix. The protein was cloned from a liver cDNA expression library of a day-9 chick embryo by virtue of its ability to bind to the F' site in the proximal promoter of the avian apoVLDLII gene. Expression of the apoVLDLII gene is completely estrogen...

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Identifiers

PMID: 10541438
DOI: 10.1089/104454999314935

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