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Article

Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin.

Proceedings of the National Academy of Sciences of the United States of America - 26 Oct 1999

Gerhard M, Lehn N, Neumayer N, Borén T, Rad R, Schepp W, Miehlke S, Classen M, Prinz C

Abstract excerpt

Infection with Helicobacter pylori is associated with different human gastric diseases. Biochemical studies, in vitro adherence assays, and in vivo animal models revealed that epithelial attachment of H. pylori can be mediated by the blood-group antigen-binding adhesin (BabA) targeting human Lewis(b) surface epitopes. Studies with transgenic mice expressing the Lewis(b) epitope have shown that such attachment can...

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Share to Adhesins, Bacterial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, Bacterial

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Source

Open in PubMed Open full text

Identifiers

PMID: 10535999
DOI: 10.1073/pnas.96.22.12778
PMCID: PMC23096

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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