Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted expression of truncated glued disrupts giant fiber synapse formation in Drosophila.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Nov 1999

Allen M J, Shan X, Caruccio P, Froggett S J, Moffat K G, Murphey R K

Abstract excerpt

Glued(1) (Gl(1)) mutants produce a truncated protein that acts as a poison subunit and disables the cytoplasmic retrograde motor dynein. Heterozygous mutants have axonal defects in the adult eye and the nervous system. Here we show that selective expression of the poison subunit in neurons of the giant fiber (GF) system disrupts synaptogenesis between the GF and one of its targets, the tergotrochanteral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Dendrites
Share to Electric Stimulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Motor Neurons

Share to Nerve Fibers

Share to Nervous System

Share to Nervous System Physiological Phenomena

Share to Synapses

Source

Open in PubMed Open full text

Identifiers

PMID: 10531442
PMCID: PMC6782895

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted expression of truncated glued disrupts giant fiber synapse formation in Drosophila.PMID 10531442Read ↗

Null mutation in shaking-B eliminates electrical, but not chemical, synapses in the Drosophila giant fiber system: a structural study.Semantic proximity Read ↗

A modifier screen in the Drosophila eye reveals that aPKC interacts with Glued during central synapse formation.Semantic proximity Read ↗

Netrin and Frazzled regulate presynaptic gap junctions at a Drosophila giant synapse.Semantic proximity Read ↗

The p150(Glued) CAP-Gly domain regulates initiation of retrograde transport at synaptic termini.Semantic proximity Read ↗

Normal dynactin complex function during synapse growth in Drosophila requires membrane binding by Arfaptin.Semantic proximity Read ↗

The Drosophila gap gene giant regulates ecdysone production through specification of the PTTH-producing neurons.Semantic proximity Read ↗

Mutant molecular motors disrupt neural circuits in Drosophila.Semantic proximity Read ↗

The nicotinic acetylcholine receptor Dalpha7 is required for an escape behavior in Drosophila.Semantic proximity Read ↗

The C. elegans gene dig-1 encodes a giant member of the immunoglobulin superfamily that promotes fasciculation of neuronal processes.Semantic proximity Read ↗

Mutations in Membrin/GOSR2 Reveal Stringent Secretory Pathway Demands of Dendritic Growth and Synaptic Integrity.Semantic proximity Read ↗

The chemical component of the mixed GF-TTMn synapse in Drosophila melanogaster uses acetylcholine as its neurotransmitter.Semantic proximity Read ↗

Presynaptic establishment of the synaptic cleft extracellular matrix is required for post-synaptic differentiation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.