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Functions and effectors of the Salmonella pathogenicity island 2 type III secretion system.

Cellular microbiology - 1 Aug 2003

Waterman Scott R, Holden David W

Abstract excerpt

Salmonella enterica uses two functionally distinct type III secretion systems encoded on the pathogenicity islands SPI-1 and SPI-2 to transfer effector proteins into host cells. A major function of the SPI-1 secretion system is to enable bacterial invasion of epithelial cells and the principal role of SPI-2 is to facilitate the replication of intracellular bacteria within membrane-bound Salmonella-containing...

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Identifiers

PMID: 12864810
DOI: 10.1046/j.1462-5822.2003.00294.x

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