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Article

Axis development: the mouse becomes a dachshund.

Current biology : CB - 21 Oct 1999

Gad J M, Tam P P

Abstract excerpt

Targeted deletion of the gene for GDF11, a novel member of the TGFbeta family, has been found to cause an increase in the number of thoracic and lumbar vertebrae in the mouse. This is the first hint that a secreted factor may influence the specification of segment identity.

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Topics

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Share to Abnormalities, Multiple
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Source

Identifiers

PMID: 10531023
DOI: 10.1016/S0960-9822(00)80013-5

Genes

GDF11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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