Article
Fusidic acid resistance determinants in Staphylococcus aureus clinical isolates.
Antimicrobial agents and chemotherapy - 1 Dec 2010
Chen Hsiao-Jan, Hung Wei-Chun, Tseng Sung-Pin, Tsai Jui-Chang, Hsueh Po-Ren, Teng Lee-Jene
Abstract excerpt
A total of 71 fusidic acid-resistant Staphylococcus aureus (45 methicillin-resistant and 26 methicillin-susceptible) isolates were examined for the presence of resistance determinants. Among 45 fusidic acid-resistant methicillin-resistant S. aureus (MRSA), isolates, 38 (84%) had fusA mutations conferring high-level resistance to fusidic acid (the MIC was ≥128 μg/ml for 22/38), none had fusB, and 7 (16%) had fusC....
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