Article
Contribution of apolipoprotein(a) size, pentanucleotide TTTTA repeat and C/T(+93) polymorphisms of the apo(a) gene to regulation of lipoprotein(a) plasma levels in a population of young European Caucasians.
Atherosclerosis - 1 Nov 1999
Valenti K, Aveynier E, Leauté S, Laporte F, Hadjian A J
Abstract excerpt
Several studies indicate that the inter-individual variation in plasma concentrations of lipoprotein(a) (Lp(a)) is mainly under genetic control. To define the effect of three DNA polymorphisms on apolipoprotein(a) (apo(a)) expression, we have determined plasma Lp(a) concentrations, apo(a) isoform size, KpnI allele size, the TTTTA pentanucleotide repeat number in the 5' control region of the apo(a) gene and the...
Topics
- Adolescent
- Adult
- Alleles
- Apolipoproteins
- Apoprotein(a)
- Enzyme-Linked Immunosorbent Assay
- Female
- Humans
- Lipoprotein(a)
- Male
- Microsatellite Repeats