Article
Impact of apo(a) length polymorphism and the control of plasma Lp(a) concentrations: evidence for a threshold effect.
Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 1998
Gaw A, Brown E A, Ford I
Abstract excerpt
Plasma lipoprotein(a) [Lp(a)] levels are believed to be controlled predominantly by the apolipoprotein(a) [APO(a)] gene, which encodes the apo(a) glycoprotein, a key constituent of the Lp(a) particle. Previously, it has been accepted that the plasma Lp(a) level is inversely proportional to apo(a) length. To examine this relationship in greater detail, 1500 unrelated, homogeneous (sex, race, age, plasma lipids)...
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