Article
Domain organization and molecular characterization of 13 two-component systems identified by genome sequencing of Streptococcus pneumoniae.
Gene - 3 Sept 1999
Lange R, Wagner C, de Saizieu A, Flint N, Molnos J, Stieger M, Caspers P, Kamber M, Keck W, Amrein K E
Abstract excerpt
In bacteria, adaptive responses to environmental stimuli are often initiated by two-component signal transduction systems (TCS). The prototypical TCS comprises two proteins: a histidine kinase (HK, hk) and a response regulator (RR rr). Recent research has suggested that compounds that inhibit two-component systems might have good antibacterial activity. In order to identify TCS that are crucial for growth or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.