Article
ConStruct: a tool for thermodynamic controlled prediction of conserved secondary structure.
Nucleic acids research - 1 Nov 1999
Lück R, Gräf S, Steger G
Abstract excerpt
A tool for prediction of conserved secondary structure of a set of homologous single-stranded RNAs is presented. For each RNA of the set the structure distribution is calculated and stored in a base pair probability matrix. Gaps, resulting from a multiple sequence alignment of the RNA set, are introduced into the individual probability matrices. These 'aligned' probability matrices are summed up to give a...
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