Article
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis.
Proceedings of the National Academy of Sciences of the United States of America - 12 Oct 1999
Arman E, Haffner-Krausz R, Gorivodsky M, Lonai P
Abstract excerpt
The aim of this study was to clarify the role of Fgfr2 during later stages of embryonic development. Of two previously reported gene-targeting experiments, the more extensive Fgfr2 deletion was lethal shortly after implantation, because of trophoblast defects, whereas the less extensive one survived until midgestation with placental insufficiency and defective limb outgrowth [Xu, X., Weinstein, M., Li, C., Naski,...
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