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Article

Neuroprotective effects of hepatoma-derived growth factor in models of Huntington’s disease

2023-02-24

Abstract excerpt

Huntington’s disease (HD) is a movement disorder caused by a mutation in the Huntingtin gene, that leads to severe neurodegeneration and inevitable death of the patients. Molecular mechanisms of HD are still not sufficiently understood, and no cure is currently available. Here, we demonstrate neuroprotective effects of hepatoma-derived growth factor (HDGF) in cellular and mouse models of HD. We show that HDGF expr...

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Identifiers and source

Literature Corpus work
40bd1803-abbf-57af-8ef1-e489e4e21f1d
DOI
10.1101/2023.02.23.529222
Open publication

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Neuroprotective effects of hepatoma-derived growth factor in models of Huntington’s diseaseDOI 10.1101/2023.02.23.529222
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