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Article

Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A.

Clinical pharmacology and therapeutics - 1 Sept 1999

Kinirons M T, O'Shea D, Kim R B, Groopman J D, Thummel K E, Wood A J, Wilkinson G R

Abstract excerpt

BACKGROUND: Cytochrome P4503A (CYP3A) activity exhibits considerable interindividual variability, and an in vivo probe to measure such differences would serve several purposes. The erythromycin breath test (ERBT) is an established approach that has proven useful in this regard, but it has several limitations. More recently, the hydroxylation of midazolam has been suggested as an alternative in vivo probe...

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Identifiers

PMID: 10511057
DOI: 10.1016/S0009-9236(99)70029-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A.PMID 10511057Read ↗

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