Article
Effect of NAT2 gene polymorphism on bladder cancer risk in Slovak population.
Molecular biology reports - 1 Feb 2011
Klimčáková Lucia, Habalová Viera, Sivoňová Monika, Nagy Vincent, Šalagovič Ján, Židzik Jozef
Abstract excerpt
N-acetyltransferase 2 (NAT2) is phase II enzyme with major roles in catalyzing the detoxification of aromatic amines, which are known risk factors for bladder cancer, and are ubiquitously present in the environment. We assessed the association between common polymorphisms in NAT2 gene and the risk of bladder cancer in 90 Slovak patients and 274 ethnicity-matched healthy controls. Effect modifications by smoking,...
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