‘Proteomic contigs’ of <i>Mycobacterium tuberculosis</i> and <i>Mycobacterium bovis</i> (BCG) using novel immobilised pH gradients

Abstract excerpt

Tuberculosis remains a major health problem throughout the world and the failure of the existing bacille Calmette-Guérin (BCG) vaccine in recent trials has prompted a search for potential replacements. Recent advances in molecular and cell biology have cast doubts on the ability of genetic analysis alone to predict polygenic human diseases and other complex phenotypes and have therefore redirected our attention...

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