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Article

Effect of deregulated IL-7 transgene expression on B lymphocyte development in mice expressing mutated pre-B cell receptors.

European journal of immunology - 1 Sept 1999

Ceredig R, Andersson J, Melchers F, Rolink A

Abstract excerpt

Deregulated overexpression of IL-7 under the control of the promoter of the Ealpha gene of MHC class II in IL-7-transgenic mice changes B cell development in wild-type mice and in mutants which limit B cell development at various cellular stages. While the introduction of deregulated IL-7 production does not change the size of the pro-B and pre-B I compartments in the bone marrow of wild-type and lambda5-/- mice,...

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Identifiers

PMID: 10508254
DOI: 10.1002/(SICI)1521-4141(199909)29:09<2797::AID-IMMU2797>3.0.CO;2-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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