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Article

Deviant trafficking of I-Ad mutant molecules is reflected in their peptide binding properties.

European journal of immunology - 1 Sept 1999

Bryant P W, Roos P, Ploegh H L, Sant A J

Abstract excerpt

I-Ad molecules harboring single amino acid changes in the conserved 80-82 region of the beta-chain show altered trafficking in invariant chain (Ii)-negative cell lines. Since residues beta81 and beta82 form hydrogen bonds with the backbone of bound peptide, alterations in this region may result i...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10508247
DOI: 10.1002/(SICI)1521-4141(199909)29:09<2729::AID-IMMU2729>3.0.CO;2-A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10508247-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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