Article
A potential role for interleukin-8 in the metastatic phenotype of breast carcinoma cells.
The American journal of pathology - 1 Feb 2001
De Larco J E, Wuertz B R, Rosner K A, Erickson S A, Gamache D E, Manivel J C, Furcht L T
Abstract excerpt
This study shows a strong correlation between the metastatic potentials of breast carcinoma cell lines and their ectopic expression of interleukin-8 (IL-8). Correlations exist for both constitutive and induced levels of IL-8 released. A correlation was also observed between cell morphology, metastatic potential, and IL-8 profile. Metastatic lines are fusiform in appearance, whereas, nonmetastatic lines are...
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